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Substance
Trenbolone Acetate
Active Dosage
100mg/ml
Form
10ml multiuse vial
Category
Injectable
Classification
Anabolic Steroid
Half Life
1-1.5 days
Dosage
Men 200-700 mg/week
Acne
Rarely
Water Retention
No
HBR
No
Aromatization
No
Hepatoxity
Yes
Description
(17beta-Hydroxyestra-4,9,11-trien-3-one)
(Trenbolone
Base + Acetate Ester)
Formula:
C20 H24 O3
Molecular
Weight: 312.4078
Molecular
Weight (base): 270.3706
Molecular
Weight (ester):60.0524
The drug
Trenbolone is, without a doubt, the most powerful injectable anabolic
steroid used by Steroid.com members to gain muscle. However the full
properties of the drug are not always fully understood. This profile
will separate fact from fiction and help steroid.com members decide
if Trenbolone is right for them.
Trenbolone is similar to the highly popular steroid Nandrolone, in
that they are both 19-nor steroids, meaning that a testosterone
molecule has been altered at the 19th position to give us a new
compound. Unlike Nandrolone however Trenbolone is an excellent mass
and hardening drug with the majority of gains being muscle fiber,
with minimal water retention (1) It has an unbelievable anabolic
(muscle building) score of 500. When you compare that to
Testosterone, which itself is a powerful mass builder, and has an
anabolic score of 100 you can begin to fathom the muscle building
potential of Trenbolone. What makes Trenbolone so anabolic?
Numerous factors come into play. Trenbolone greatly
increases the level of the extremely anabolic hormone IGF-1 within
muscle tissue (2). And, its worth noting that not only does it
increase the levels of IGF-1 in muscle over two fold, it also causes
muscle satellite cells (cells that repair damaged muscle) to be more
sensitive to IGF-1 and other growth factors(3). The amount of DNA per
muscle cell may also be significantly increased (3).
Trenbolone also has a very strong binding
affinity to the androgen receptor (A.R), binding much more strongly
than testosterone (4). This is important, because the stronger a
steroid binds to the androgen receptor the better that steroid works
at activating A.R dependent mechanisms of muscle growth. There is
also strong supporting evidence that compounds which bind very
tightly to the androgen receptor also aid in fat loss. Think as the
receptors as locks and androgen's as different keys, with some keys
(androgen's) opening (binding) the locks (receptors) much better than
others. This is not to say that AR-binding is the final word on a
steroids effectiveness. Anadrol doesnt have any measurable binding to
the AR& and we all know how potent Anadrol is for mass-building.
Trenbolone increases nitrogen retention in muscle
tissue (5). This is of note because nitrogen retention is a strong
indicator of how anabolic a substance is. However, it's incredible
mass building effects do not end there. Trenbolone has the ability to
bind with the receptors of the anti-anabolic (muscle destroying)
glucocorticoid hormones (6). This may also has the effect of
inhibiting the catabolic (muscle destroying) hormone cortisol (7).
Yet another amazing trait that must be noted is its ability to
improve feed efficiency and mineral absorption in animals given the
drug (8). To help you understand what this means for you, feed
efficiency is a measurement of how much of an animals diet is
converted into meat, and the more food it takes to produce this meat,
the lower the efficiency. Conversely, the less food it takes to
produce meat the, higher the efficiency& well you get the idea.
Animals given Trenbolone gained high quality weight without having
their diet adjusted, thus improving feed efficiency. Finding new
compounds which can improve feed efficiency is a billion dollar
industry, and has spawned many nutritional advances in the
bodybuilding world over the last few decades (CLA, Whey Protein, and
HMB are compounds which spring to mind as having first been
introduced by the livestock industry). What does this translate to
for the hard training athlete? The food you eat will be better
utilized for building lean muscle, and vitamins and minerals are also
better absorbed which may keep you healthier during cycle.
Trenbolone is also a highly androgenic hormone, when compared with
Testosterone, which has an androgenic ratio of 100; Trenbolone's
androgenic ratio is an astonishing 500. Highly androgenic steroids
are appreciated for the effects they have on strength as well as
changing the estrogen/androgen ratio, thus reducing water and under
the skin. As if the report on Trenbolone was not good enough, it gets
better; Trenbolone is extraordinarily good as a fat
loss agent. One reason for this is its powerful effect on nutrient
partitioning (9). It is a little known fact is that androgen
receptors are found in fat cells as well as muscle cells(10),
androgens act directly on the A.R in fat cells to affect fat
burning.(11) the stronger the androgen binds to the A.R, the higher
the lipolytic (fat burning) effect on adipose tissue (fat)(11). Since
some steroids even increase the numbers of A.R in muscle and fat (11,
12) this fat loss effect would be amplified with the concurrent use
of other compounds, such as Testosterone.
Trenbolone promotes red blood cell production and
increases the rate of glycogen replenishment, significantly improving
recovery (13). Like almost all steroids, it's effects are dose
dependant with higher dosages having the greatest effects on body
composition and strength. Mental changes are a notorious side effect
of Trenbolone use (15), androgens increase chemicals
in the brain that promote aggressive behavior(16), which can be
beneficial for some athletes wanting to improve speed and power.
Trenbolone's chemical structure makes it resistant to the
aromatize enzyme (conversion to estrogen) thus absolutely no
percentage of Trenbolone will convert to estrogen.
Trenbolone administration would not promote estrogenic side effects
such as breast tissue growth in men (gynecomastia, bitch tits)
accelerated fat gain, decline in fat break down and water retention.
Trenbolone is also resistant to the 5-
alpha-reductase enzyme, this enzyme reduces some steroid hormones
into a more androgenic form, in this case however this does not
matter. Trenbolone boasts an androgenic ratio of 500. It can easily
cause adverse androgenic side effects in people who are prone to hair
loss, prostate enlargement, oily skin and acne. Unfortunately
Trenbolone's potential negative side effects do not end there.
Trenbolone is also a noted progestin: it binds to the receptor of the
female sex hormone progesterone (with about 60% of the actual
strength progesterone) (17). In sensitive people this can lead to
bloat and breast growth worse still, Trenbolone's active metabolite
17beta-trenbolone has a binding affinity to the progesterone receptor
(PgR) that is actually greater than progesterone itself (18). No need
to panic though, the anti-estrogens letrzole or fulvestrant can lower
progesterone levels, and combat any progestenic sides. The use of a
19-nor compound like trenbolone also increases prolactin & .
bromocriptine or cabergoline are often recommended to lower prolatin
levels (20). Testicular atrophy (shrunken balls) may also occur; HCG
used intermittently throughout a cycle can prevent this. (21) It is
also wise for Tren users to closely monitor their cholesterol levels,
as well as kidney function and liver enzymes, as Tren has the
potential to negatively affect all of those functions. Finaplix,
being a powerful progestin, will also shut down natural testosterone
production which even a relatively small dose and keep the
testosterone level suppressed for an extended period of time, this
can lower libido and cause erectile dysfunction (fina dick). It is
essential that you always stack Finaplix with testosterone.
The acetate ester is a very short-chain ester attached to the
Finaplix molecule. It has an active life of 2-3 days but to keep
blood levels of trenbolone elevated and steady, daily injections are
often recommended. The acetate ester provides a rapid and high
concentration of the hormone which is beneficial to those seeking
quick gains, coupled with a rapid clearing time the acetate ester can
be discontinued on the onset of adverse side effects.